diff --git a/include/nana/gui/widgets/listbox.hpp b/include/nana/gui/widgets/listbox.hpp
index ac3fc9f7..717d6d91 100644
--- a/include/nana/gui/widgets/listbox.hpp
+++ b/include/nana/gui/widgets/listbox.hpp
@@ -1593,6 +1593,16 @@ the nana::detail::basic_window member pointer scheme
 		 * @return index_pairs containing all visible items.
 		 */
 		index_pairs visibles() const;
+
+		/// Sets a predicate that indicates whether to deselect items when mouse_up is triggered.
+		/**
+		 * The predicate is called before the listbox attempts to deselect the selected items in the mouse_up event. Other situations,
+		 * the predicates isn't called, for example, releasing mouse button after user performed a box selection, because listbox doesn't deselect the items during this operation.
+		 * @param predicate Decides to deselect the items.
+		 *	The paramater of predicate indicates the mouse button which is releasing.
+		 *	It returns true to deselect the selected items. It returns false to cancel to deselect the selected items.
+		 */
+		void set_deselect(std::function<bool(nana::mouse)> predicate);
 	private:
 		drawerbase::listbox::essence & _m_ess() const;
 		nana::any* _m_anyobj(size_type cat, size_type index, bool allocate_if_empty) const override;
diff --git a/source/gui/widgets/listbox.cpp b/source/gui/widgets/listbox.cpp
index f387140f..9d372746 100644
--- a/source/gui/widgets/listbox.cpp
+++ b/source/gui/widgets/listbox.cpp
@@ -2011,6 +2011,8 @@ namespace nana
 
 				std::function<void(paint::graphics&, const rectangle&, bool)> ctg_icon_renderer;	///< Renderer for the category icon
 
+				std::function<bool(nana::mouse)> pred_msup_deselect;
+
 				struct operation_rep
 				{
 					operation_states state{operation_states::none};
@@ -4470,7 +4472,10 @@ namespace nana
 					if (operation_states::msup_deselect == essence_->operation.state)
 					{
 						essence_->operation.state = operation_states::none;
-						need_refresh |= essence_->lister.select_for_all(false, essence_->operation.item);
+
+						//Don't deselect if the predicate returns false
+						if(!(essence_->pred_msup_deselect && !essence_->pred_msup_deselect(arg.button)))
+							need_refresh |= essence_->lister.select_for_all(false, essence_->operation.item);
 					}
 
 					if (need_refresh)
@@ -6102,6 +6107,11 @@ namespace nana
 			return indexes;
 		}
 
+		void listbox::set_deselect(std::function<bool(nana::mouse)> predicate)
+		{
+			_m_ess().pred_msup_deselect = std::move(predicate);
+		}
+
 		drawerbase::listbox::essence & listbox::_m_ess() const
 		{
 			return get_drawer_trigger().ess();